ArticleFrontiers in veterinary science2026
Natural eggshell membrane supplementation for chronic lameness in warmblood horses: a 12-week prospective before-after study.
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Osteoarthritis is a leading cause of equine lameness, yet pragmatic evidence for nutraceuticals in horses remains limited. Methods: We prospectively evaluated 12 weeks of daily natural eggshell membrane (NEM; 12 mg/kg, orally) supplementation in Warmblood horses with chronic lameness using a single-arm before-after design. Ten horses were enrolled and prespecified paired contrasts compared visit 3 (V3, week 12) with baseline (V1). Outcomes included rider-reported under-saddle function (walk and trot), examiner-graded lameness (rest and walk-trot composite), simple joint-angle kinematics (degrees), and owner-rated palatability. Results: Rider-reported function improved by approximately half a grade at both walk and trot, and owner-rated palatability improved markedly. Examiner walk-trot scores showed a small trend toward improvement, while rest lameness remained unchanged. Statistical inference supported these patterns, with 95% confidence intervals (CIs) excluding zero for rider scores (Δ = -0.50) and palatability (Δ = -1.50). Moderate changes were observed in right-fore joint angle (Δ = +3.06°) and examiner composite grades (Δ = -0.11). These effects were supported by small-sample inference (permutation tests, bootstrap CIs) and complementary Bayesian estimation. Discussion and conclusion: NEM showed potential short-term improvements in owner-reported function and examiner-graded gait, but larger controlled studies are needed.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.