ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2026
[Clinical Manifestations of Childhood Systemic Lupus Erythematosus-associated Acute Pancreatitis and Evaluation of the Efficacy of Plasma Exchange Combined With Glucocorticoids].
Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: To summarize and analyze the clinical manifestations of acute pancreatitis associated with childhood systemic lupus erythematosus (cSLE) and to evaluate the therapeutic efficacy of plasma exchange combined with glucocorticoids. Methods: This retrospective study analyzed clinical data from cSLE patients diagnosed and treated at West China Second University Hospital from January 2018 to December 2020. Patients were divided into a pancreatitis group (diagnosed with cSLE-associated acute pancreatitis) and a non-pancreatitis group (without this diagnosis), and differences between groups were compared. Results: Among 170 cSLE patients enrolled, 9 were in the pancreatitis group and 161 were in the non-pancreatitis group. The median SLEDAI score was 24.0 (P25-P75: 20.5-29.0) in the pancreatitis group and 18.0 (P25-P75: 14.0-20.0) in the non-pancreatitis group, with a statistically significant difference ( Conclusion: Acute pancreatitis is a rare but severe complication of cSLE, with higher SLEDAI scores correlating with increased risk of pancreatitis. Early diagnosis and aggressive treatment with glucocorticoids combined with plasma exchange may be associated with improved short-term outcomes.
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