Evidence map›Paper›PMID 41834973›Full record

ReviewSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2026

[Recent Research Progress and Prospects on Periodontitis Affecting Systemic Comorbidities via the Oral-Gut Axis].

Shuwei Zhang, Yuchao Li, Ze Yang, Haifeng Huang, Yaping Pan

Abstract readReviewEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Review in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuwei Zhang（ 110002）Department of Periodontics, School and Hospital of Stomatology, China Medical University, Shenyang 110002, China.ORCID 0000-0002-6296-7239
Yuchao Li（ 110002）Department of Periodontics, School and Hospital of Stomatology, China Medical University, Shenyang 110002, China.
Ze Yang（ 110002）Department of Periodontics, School and Hospital of Stomatology, China Medical University, Shenyang 110002, China.
Haifeng Huang（ 110002）Department of Periodontics, School and Hospital of Stomatology, China Medical University, Shenyang 110002, China.
Yaping Pan（ 110002）Department of Periodontics, School and Hospital of Stomatology, China Medical University, Shenyang 110002, China.ORCID 0000-0001-6711-8992

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis is a prevalent chronic infectious and inflammatory disease worldwide, which imposes harms extending far beyond the oral cavity. A large body of research has demonstrated that periodontitis is closely associated with various systemic diseases, such as diabetes mellitus, cardiovascular diseases, inflammatory bowel disease, and rheumatoid arthritis. Serving as a crucial pathway connecting the oral cavity to the entire body, the oral-gut axis becomes the core mechanism through which periodontitis affects systemic health, primarily via the ectopic colonization of salivary microbiota, intestinal dysbiosis, intestinal barrier disruption, and systemic inflammation. This review summarizes recent studies focusing on how periodontitis influences systemic comorbidities via the oral-gut axis, encompassing clinical studies, animal experimental and

Indexed as

Gastrointestinal MicrobiomeMouthPeriodontitisAnimalsArthritis, RheumatoidCardiovascular DiseasesComorbidityDiabetes MellitusDysbiosisHumansInflammatory Bowel DiseasesEctopic colonizationGut microbiomeOral-gut axisPeriodontitisReviewSystemic comorbidities

Identifiers

PMID41834973
PMCPMC12980081

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.