ArticleInfection and drug resistance2026
Prevalence and Antimicrobial Resistance of
Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Purpose: To investigate the clinical distribution and resistance trends of Patients and Methods: A retrospective analysis was performed on non-duplicate KP isolates obtained from pediatric patients (aged ≤14 years) at Guangdong Women and Children Hospital (2015-2024). Time trends of isolated rates and resistance rates for the KP strains were analyzed using Joinpoint regression, with statistical analysis performed in SPSS and Python. Results: A total of 2907 non-duplicate KP isolates from 2557 patients were analyzed. The proportion of KP among all clinical isolates decreased significantly from 18.4% (492/2670) in 2015 to 6.5% (203/3135) in 2024 ( Conclusion: Despite a decreasing overall prevalence of KP, the persistent high prevalence of ESBL-KP and the rapidly increasing trend of CRKP in the PICU suggested that recalibrated, unit-specific antimicrobial strategies were necessary. This study provides supporting information for the rational use of antimicrobial agents in clinical practice based on the comprehensive investigation of antimicrobial resistance change.
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