Evidence map›Paper›PMID 41835537›Full record

ArticleACS omega2026

Building a Simple Platform for Tailoring Peptide Surface Chemistry to Enhance Cellular Uptake of Polymer-Coated Gold Nanoparticles.

Ilya Kotelnikov, Gabriela Borba Mondo, Caroline Arana da Silva Ribeiro, Maria Mercedes Rolon Sosa, Wendel Andrade Alves, Bruno Lemos Batista, Ognen Pop-Georgievski, Vladimir Proks, Cristiano Giacomelli, Fernando Carlos Giacomelli

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In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ilya KotelnikovInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Prague 162 00, Czech Republic.
Gabriela Borba MondoCentro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André 09280-560, Brazil.
Caroline Arana da Silva RibeiroCentro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André 09280-560, Brazil.
Maria Mercedes Rolon SosaCentro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André 09280-560, Brazil.
Wendel Andrade AlvesCentro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André 09280-560, Brazil.ORCID https://orcid.org/0000-0002-8394-2751
Bruno Lemos BatistaCentro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André 09280-560, Brazil.
Ognen Pop-GeorgievskiInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Prague 162 00, Czech Republic.ORCID https://orcid.org/0000-0001-7938-9271
Vladimir ProksInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Prague 162 00, Czech Republic.ORCID https://orcid.org/0000-0001-7368-7120
Cristiano GiacomelliDepartamento de Química, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria 97105-900, Brazil.
Fernando Carlos GiacomelliCentro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André 09280-560, Brazil.ORCID https://orcid.org/0000-0002-6872-9354

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotherapeutic delivery requires particulate systems composed of only a few components yet featuring multiple capabilities to reach the clinic. In this study, we built a platform based on selective reactions (solid-phase peptide synthesis, peptide coupling chemistry, and click chemistry) to enhance cellular uptake of gold nanoparticles (AuNPs) by anchoring cell-penetrating peptides (CPPs) at the outermost layer of the constructs. Model amphipathic peptide (MAP), trans-acting activator of transcription (TAT), hexarginine (R

Identifiers

PMID41835537
PMCPMC12980161

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.