Evidence map›Paper›PMID 41835563›Full record

ArticleACS omega2026

Extraction of Lycopene from Tomato Peels Using Supercritical Carbon Dioxide and Conjugation of the Extracted Lycopene with TiO

Farid Hajareh Haghighi, Roya Binaymotlagh, Lionel Nguemna Tayou, Marianna Villano, Laura Chronopoulou, Cleofe Palocci

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In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Farid Hajareh HaghighiDepartment of Chemistry, Sapienza University of Rome, Piazzale Aldo Moro 5, Rome 00185, Italy.
Roya BinaymotlaghDepartment of Chemistry, Sapienza University of Rome, Piazzale Aldo Moro 5, Rome 00185, Italy.
Lionel Nguemna TayouDepartment of Chemistry, Sapienza University of Rome, Piazzale Aldo Moro 5, Rome 00185, Italy.
Marianna VillanoDepartment of Chemistry, Sapienza University of Rome, Piazzale Aldo Moro 5, Rome 00185, Italy.ORCID https://orcid.org/0000-0003-4517-1148
Laura ChronopoulouDepartment of Chemistry, Sapienza University of Rome, Piazzale Aldo Moro 5, Rome 00185, Italy.
Cleofe PalocciDepartment of Chemistry, Sapienza University of Rome, Piazzale Aldo Moro 5, Rome 00185, Italy.ORCID https://orcid.org/0000-0001-5583-8941

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tomato processing industry is one of the most widespread food manufacturing sectors globally, generating substantial amounts of residue, including tomato skins, peels, seeds, and vascular tissues. These residues still retain valuable bioactive compounds (e.g., carotenoids like lycopene), essential for food, pharmaceutical, and nutraceutical applications. Currently, traditional solvent extraction is the most common method for retrieving these compounds from tomato residue. However, this approach has notable disadvantages, including high solvent consumption and difficulties in utilizing leftover biomass. To address these issues, innovative technologies have introduced modifications to process configurations and techniques that alter or break down plant cells, significantly improving compound recovery. Supercritical fluid extraction offers an effective method for enhancing the value of tomato residues before disposal, as it is an environmentally friendly approach, particularly when carbon dioxide is used as the extraction solvent. The novelty of the present work is the specific optimization and integration of this green extraction technique with the subsequent conjugation of the extracted lycopene to TiO

Identifiers

PMID41835563
PMCPMC12980429

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.