Evidence map›Paper›PMID 41835598›Full record

ArticleACS omega2026

Taraxasterol Acetate Attenuates TNF-α-Induced Insulin Resistance via Regulation of Insulin Signaling, Inflammation, and Lipid Metabolism in 3T3-L1 Cells.

Renan P de Lima, Francisca Tuelly B de Oliveira, Ana Virginia L da Silva, Maria Rose Jane R Albuquerque, Otília D L Pessoa, Flávia A Santos

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Renan P de LimaDepartment of Medicine, Weill Center for Metabolic Health, Cardiovascular Research Institute, Weill Cornell Medicine, New York, New York 10021, United States.ORCID https://orcid.org/0000-0001-9653-7037
Francisca Tuelly B de OliveiraDepartment of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará 60430-270, Brazil.
Ana Virginia L da SilvaDepartment of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará 60430-270, Brazil.
Maria Rose Jane R AlbuquerqueVale do Acaraú State University, Sobral, Ceará 62010-295, Brazil.
Otília D L PessoaDepartment of Organic and Inorganic Chemistry, Sciences Center, Federal University of Ceará, Fortaleza, Ceará 60440-900, Brazil.ORCID https://orcid.org/0000-0002-1617-7586
Flávia A SantosDepartment of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará 60430-270, Brazil.ORCID https://orcid.org/0000-0003-3625-8540

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulin resistance, obesity, and type 2 diabetes mellitus (T2DM) are interrelated metabolic disorders with rising global prevalence. Triterpenes, known for their diverse pharmacological properties, have shown potential in improving insulin sensitivity and exerting antidiabetic and antiobesity effects. This study evaluated the effects of taraxasterol acetate (TXA), a pentacyclic triterpene isolated from

Identifiers

PMID41835598
PMCPMC12980172

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.