ArticleInternational journal of general medicine2026
Predictive Value of NLR, PLR, RDW and PDW in the Adverse Prognosis of Neonatal Pneumonia.
Article in International journal of general medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Neutrophil-to-lymphocyte ratio (NLR), Platelet-to-lymphocyte ratio (PLR), Red-cell-distribution width (RDW) and Platelet-distribution width(PDW) have been proved to be related to the severity of a variety of diseases and poor prognosis. But their predictive value in neonatal pneumonia is still unknown. Therefore, this study explored the predictive value of NLR, PLR, RDW and PDW in the adverse prognosis of neonatal pneumonia. Methods: We retrospectively analyzed 132 neonates with pneumonia treated in our hospital from April 2022 to October 2024. At the same time, 50 healthy newborns delivered in our hospital during the same period were selected as the control group. The levels of NLR, PLR, RDW and PDW in children with different disease severity and prognosis were analyzed; The correlation between NLR, PLR, RDW, PDW levels and disease severity was analyzed, and the predictive value for the adverse prognosis of neonatal pneumonia. Results: Among 132 children, 65 were mild, 44 moderate and 23 severe; 26 cases had poor prognosis. The levels of NLR, PLR, RDW and PDW in children with different disease severity were significantly different (P<0.05). Spearman test showed that NLR, PLR, RDW, PDW were significantly positively correlated with the severity of neonatal pneumonia (P<0.05). Multivariate logistic regression analysis showed that NLR, PLR, RDW and PDW were the related factors influencing the poor prognosis of neonatal pneumonia (p<0.05). ROC curve analysis showed that the value of combined prediction of four indicators for poor prognosis of neonatal pneumonia was higher than that of single indicators, and the sensitivity of combined prediction was 100%, and the specificity was 94.9%. Conclusion: NLR, PLR, RDW, PDW were positively correlated with the severity of neonatal pneumonia, and the value of combined prediction of poor prognosis was higher.
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