ArticleCJC open2026
Obstructive Sleep Apnea Is Associated with Increased Myocardial Scar Burden in Patients with Obstructive Hypertrophic Cardiomyopathy.
Article in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Background: Obstructive sleep apnea (OSA) is frequent in patients with hypertrophic cardiomyopathy (HCM). Late gadolinium enhancement (LGE) reflects myocardial scarring, which is significantly associated with adverse clinical events in patients with HCM. However, whether OSA is associated with increased myocardial scar burden in these patients remain unclear. Methods: We prospectively studied 223 consecutive patients with obstructive HCM at Fuwai and Anzhen Hospitals between September 2018 and 2023. All patients underwent polysomnography and cardiac magnetic resonance (CMR) imaging. Results: Myocardial scarring (quantified by LGE%, LGE, % of LV mass) increased with OSA severity ( Conclusions: After adjusting for clinical variables, AHI, OSA presence, and severity were associated with increased myocardial scar burden (reflected by LGE%) in patients with obstructive HCM. Further clinical trials are needed to assess whether OSA treatment reduces adverse clinical events in this population.
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