Evidence map›Paper›PMID 41836362›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2026

Association of NLRP3 Inflammasome rs10754558 Polymorphism with Type 2 Diabetes Mellitus and Its Complications: Clinical and Bioinformatics Study.

Ahmed M Ahmed, Hakeemah H Al-Nakhle, Abdulmannan M Aman, Amjad M Yousuf, Abdel Rahim M Muddathir, Yahya A Almutawif, Saber M Eweda, Awadh S Alsubhi, Hashim M Aljohani, Renad M Alhamawi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Integrative Clinical and Functional Characterization of theDiagnostics (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ahmed M AhmedDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.ORCID 0000-0002-9842-9678
Hakeemah H Al-NakhleDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.
Abdulmannan M AmanDepartment of General Medicine, University Medical Center, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.
Amjad M YousufDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.
Abdel Rahim M MuddathirDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.
Yahya A AlmutawifDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.
Saber M EwedaDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.
Awadh S AlsubhiDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.
Hashim M AljohaniDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.
Renad M AlhamawiDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.
Faisal AlmalkiDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.
Zakaria EltahirDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The Methods: In this case control study, 250 T2DM cases and 150 matched-age and gender healthy subjects were genotyped for rs10754558. Clinical, biochemical, and inflammatory markers ( Results: T2DM cases had a significantly higher frequency of the rs10754558 C allele than controls (20.8% vs 13.3%, p = 0.007). Nephropathy/CVD were significantly associated with the CC genotype (83.3%, p < 0.001). Higher levels of Conclusion: The

Indexed as

IL-1βinflammasomemiRNANLRP3rs10754558T2DM

Identifiers

PMID41836362
PMCPMC12988750

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.