ArticleJournal of pain research2026
Early Postoperative Pain and Its Risk Factors in Patients Undergoing Total Knee Arthroplasty Under the ERAS Protocol.
Article in Journal of pain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Popliteal Plexus Block as a Potential Alternative to IPACK Block in Total-Knee Arthroplasty: Anatomical Rationale, Clinical Evidence, and Ergonomic Advantages.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Enhanced Recovery After Surgery (ERAS) is a multidisciplinary, evidence-based protocol designed to accelerate patient recovery after surgery. While applied to total knee arthroplasty (TKA) to optimize perioperative care, a significant risk of early postoperative pain persists. This study aims to investigate the current status and identify key high-risk factors for early pain in TKA patients under ERAS, facilitating the development of targeted strategies to alleviate pain and enhance recovery. Methods: We conducted a retrospective analysis of 183 patients who underwent TKA under the ERAS protocol at our hospital. On postoperative day 3, patients were categorized using the Numerical Rating Scale (NRS): those with NRS scores ≤3 formed the mild pain group (n=132), and those with scores >3 constituted the moderate-to-severe pain group (n=51). Clinical data were compared, and univariate along with multivariate logistic regression analyses were employed to identify independent risk factors for early postoperative pain. Results: Of the 183 patients, 51 (27.87%) experienced moderate-to-severe pain. Comparative analysis revealed significant differences between the two groups in intraoperative tourniquet time, preoperative Hamilton Anxiety Scale (HAMA) score, preoperative quadriceps thickness, and preoperative Knee Society Score (KSS). Multivariate analysis confirmed these four factors as independent risk factors. A predictive nomogram model built on these factors demonstrated good calibration and a high predictive value, with an Area Under the Curve (AUC) of 0.892. Furthermore, NRS scores showed a positive correlation with tourniquet time and HAMA scores, and a negative correlation with quadriceps thickness and KSS scores. Conclusion: A notable proportion of TKA patients under ERAS still experience moderate-to-severe early postoperative pain. This pain is independently associated with longer tourniquet time, higher preoperative anxiety, thinner quadriceps, and lower preoperative KSS. These factors are valuable for predicting pain, enabling early targeted interventions to minimize its occurrence and promote recovery.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.