Evidence mapPaperPMID 41837586Full record

ArticleThe Journal of physiology2026

Sarcolemmal and mitochondrial membrane potentials measured ex vivo and in vivo in the heart by pharmacokinetic modelling of [

Edward C T Waters, Friedrich Baark, Matthew R Orton, Michael J Shattock, Richard Southworth, Thomas R Eykyn

Abstract read
In one paragraph

Article in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edward C T WatersSchool of Biomedical Engineering and Imaging Sciences, King's College London, The Rayne Institute, St Thomas' Hospital, London, UK.
Friedrich BaarkSchool of Biomedical Engineering and Imaging Sciences, King's College London, The Rayne Institute, St Thomas' Hospital, London, UK.
Matthew R OrtonDepartment of Radiology, MRI Unit, The Royal Marsden NHS Foundation Trust, London, UK.
Michael J ShattockSchool of Cardiovascular and Metabolic Medicine and Sciences, King's College London, London, UK.ORCID 0000-0001-6242-7585
Richard SouthworthSchool of Biomedical Engineering and Imaging Sciences, King's College London, The Rayne Institute, St Thomas' Hospital, London, UK.ORCID 0000-0002-7904-8335
Thomas R EykynSchool of Biomedical Engineering and Imaging Sciences, King's College London, The Rayne Institute, St Thomas' Hospital, London, UK.ORCID 0000-0003-1768-3808

Funding

British Heart Foundation RE/24/130035British Heart Foundation RG/12/4/29426British Heart Foundation RG/17/15/33106Engineering and Physical Sciences Research Council EP/S019901/1Engineering and Physical Sciences Research Council EP/S032789/1National Institute for Health Research (NIHR)Wellcome EPSRC Centre for Medical Engineering WT203148/Z/16/Z
6 · The paper itself

Abstract

Transmembrane electrical potentials across the sarcolemmal (

Indexed as

HeartMembrane Potential, MitochondrialRadiopharmaceuticalsSarcolemmaTechnetium Tc 99m SestamibiAnimalsCarbonyl Cyanide m-Chlorophenyl HydrazoneMaleMitochondria, HeartOrganophosphorus CompoundsRatsRats, Sprague-DawleyRats, WistarCarbonyl Cyanide m-Chlorophenyl HydrazoneOrganophosphorus CompoundsRadiopharmaceuticalsTechnetium Tc 99m Sestamibi[99mTc]sestamibi pharmacokineticsheartmitochondrial dysfunctionmitochondrial membrane potentialsarcolemmal membrane potentialtechnetium‐labelled membrane potential probe

Identifiers

PMID41837586
PMCPMC13039287

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.