Evidence map›Paper›PMID 41837692›Full record

ReviewThe Journal of physiology2026

TMEM16A channel signalling microdomains in the regulation of vascular function.

Fênix Araujo, Swapnil K Sonkusare

Abstract readReview
In one paragraph

Review in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fênix AraujoRobert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA.
Swapnil K SonkusareRobert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA.

Funding

Paracrine TNF signaling impairs endothelial TRPV4 microdomains in obesityR01HL142808 · NHLBI · UNIVERSITY OF VIRGINIA · PI Swapnil K. Sonkusare · 2019 to 2026
$4.4M
Flow-Activated Calcium Signaling Microdomains in Small Pulmonary ArteriesR01HL146914 · NHLBI · UNIVERSITY OF VIRGINIA · PI Swapnil K. Sonkusare · 2019 to 2026
$3.8M
Novel Calcium Signaling Nanodomains in Vascular Smooth Muscle CellsR01HL167208 · NHLBI · UNIVERSITY OF VIRGINIA · PI Swapnil K. Sonkusare · 2023 to 2026
$2.1M
American Heart Association 26POST1565429NHLBI NIH HHS R01 HL142808NHLBI NIH HHS R01 HL146914NHLBI NIH HHS R01 HL167208NIH HHS HL142808NIH HHS HL146914NIH HHS HL167208
6 · The paper itself

Abstract

Among the various chloride channel subtypes expressed in vascular tissues, Ca

Indexed as

calcium channelscalcium signallingchloride channelsendotheliumTMEM16Avascular smooth musclevasoconstriction

Identifiers

PMID41837692
PMCPMC13634485

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.