Trial reportPhysiological reports2026
Renal effects of short-term ketone monoester supplementation in healthy adults: A randomized, placebo-controlled study.
Trial report in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Recent studies suggest potential benefits of ketosis. However, research is lacking on its effects on renal physiology. This study aimed to investigate the renal effects of short-term exogenous ketosis in healthy adults, focusing on glomerular function and electrolyte handling. In a double-blind, placebo-controlled, randomized crossover trial, 15 healthy participants received ketone monoester (KME) or placebo three times daily for 5 days under a standardized diet, separated by a 2-week washout. On the fifth day of each intervention, participants collected a 24-h urine sample. The following day, glomerular filtration rate (GFR) was assessed with
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.