Observational studyAmerican journal of reproductive immunology (New York, N.Y. : 1989)2026
Maternal Obesity Modulates Postpartum Inflammatory and Hormonal Profiles, Without Detectable Differences in Tested Redox Markers.
Observational study in American journal of reproductive immunology (New York, N.Y. : 1989), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
problemMaternal obesity is associated with elevated inflammatory markers, hormonal dysregulation, and metabolic disturbances. However, how maternal obesity modulates systemic inflammatory, hormonal, and redox profiles in the peripartum and postpartum periods remains incompletely understood. METHOD OF STUDY: This observational study evaluated inflammatory biomarkers, steroid hormone levels, and oxidative stress markers in obese (n = 8) and non-obese (n = 11) pregnant women undergoing labor induction. Peripheral maternal blood samples were collected immediately before induction and again within approximately 5-10 mins after delivery. Placental tissue was collected postpartum within the same interval. Comparative analyses between groups and time points were performed using repeated-measures statistical models.
resultsC-reactive protein (CRP) levels increased postpartum only in the obese group, indicating an enhanced inflammatory response after delivery. In contrast, interleukin-6 (IL-6) levels declined postpartum only in the non-obese group. No between-group differences were detected in the oxidative stress markers assessed, either in maternal blood or placental tissue.
conclusionsMaternal obesity is associated with distinct postpartum inflammatory and hormonal profiles, characterized by sustained CRP elevation and altered cytokine dynamics. No between-group differences were detected in the redox markers assessed, suggesting preserved redox balance in the parameters evaluated. These findings highlight the importance of considering postpartum immune modulation in obese parturients and support further investigation into obesity-associated inflammatory regulation during the peripartum period.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.