ArticleJournal of clinical biochemistry and nutrition2026
Antioxidant polymer nanoparticles ameliorate cancer cachexia via intestinal ROS scavenging.
Article in Journal of clinical biochemistry and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Controlling systemic disease from the gut: intestinal ROS as an upstream driver of systemic inflammation.Journal of clinical biochemistry and nutrition · 2026Review
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2 authors.
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Abstract
Cancer cachexia affects approximately 80% of patients with advanced cancer, leading to anorexia, weight loss, and severe muscle wasting that negatively impacts survival. Despite its clinical significance, no effective therapies have been approved worldwide. Inflammatory cytokines, particularly interleukin-6 (IL-6), are known to play a key role in the pathogenesis of cachexia and represent promising therapeutic targets. In this study, we explored the role of intestinal oxidative stress in regulating systemic inflammation associated with cancer cachexia. We orally administered antioxidant polymer nanoparticles (siSMAPo
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