Evidence map›Paper›PMID 41841683›Full record

Trial reportTranslational vision science & technology2026

Effect of Duration of Spectacle Lenses With Highly Aspherical Lenslets Wear on Choroidal Thickness in Low-Hyperopic Chinese Children.

Zhe Zhang, Zhirong Zhang, Yanze Yu, Bingjie Wang, Pauline Kang, Kathleen Watt, Xiaoying Wang, Xingtao Zhou, Zhi Chen

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Translational vision science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhe ZhangEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Zhirong ZhangEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Yanze YuEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Bingjie WangSchool of Optometry and Vision Science, University of New South Wales, Sydney, NSW, Australia.
Pauline KangSchool of Optometry and Vision Science, University of New South Wales, Sydney, NSW, Australia.
Kathleen WattSchool of Optometry and Vision Science, University of New South Wales, Sydney, NSW, Australia.
Xiaoying WangEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Xingtao ZhouEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Zhi ChenEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to evaluate the effects of spectacle lenses with highly aspherical lenslets (HALs) in children with low hyperopia, focusing on their impact on choroidal thickness (ChT) and axial length (AL) elongation. Methods: A single-center, randomized, controlled trial was conducted from August 2022 to September 2023, involving children aged 6 to 9 years with spherical equivalent ranging from +0.00 to +2.00 diopters (D). Participants were randomly assigned to either a single-vision lens (SVL) group or a HAL spectacle lens group. AL and ChT were measured at baseline, 1 month, and 12 months. ChT changes were analyzed with average weekly wearing time of spectacle lenses and 12-month AL elongation. Results: A total of 84 children (44 in the SVL group and 40 in the HAL group) completed the 12-month follow-up visit and were included in the analysis. There was no significant change in mean ChT from baseline in either group (both P > 0.05). However, there was a positive correlation between weekly lens wearing time (38.6 ± 18.5 hours) and subfoveal ChT change (325.0 ± 37.1 µm) in the HAL group (R2 = 0.46, P < 0.0001), which was inversely correlated with axial elongation (0.19 mm; interquartile range, 0.12-0.27; R2 = 0.13; P = 0.004). In contrast, no significant correlations were observed in the SVL group. Conclusions: No significant differences were observed between HAL and single-vision spectacles in AL or ChT change. However, HAL spectacle lenses influenced AL elongation and subfoveal ChT with a dose-dependent effect related to lens wearing time in low hyperopic Chinese children. Translational Relevance: Spectacle lenses with highly aspherical lenslets slow axial elongation by modulating choroidal thickness in low-hyperopic children.

Indexed as

ChoroidEyeglassesHyperopiaAxial Length, EyeChildChinaEast Asian PeopleFemaleHumansMaleRefraction, OcularTime FactorsTomography, Optical CoherenceVisual Acuity

Identifiers

PMID41841683
PMCPMC13007415

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.