ArticlePediatric cardiology2026
Diastolic Function Unchanged After Lifestyle Intervention Despite Improved VO
Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pediatric heart transplant recipients commonly exhibit diastolic dysfunction, which may contribute to reduced exercise capacity. In our Healthy Hearts study, a supervised exercise and nutrition intervention improved exercise performance and endothelial function. We hypothesized that this intervention would also improve resting echocardiographic markers of diastolic function in this cohort. Fourteen stable heart transplant patients aged 8 to 19 years, at least one year post-transplant, participated in a live-video-supervised exercise and nutrition intervention from 2014 to 2018. Participants completed a 12-16-week intervention, followed by a maintenance phase of similar duration with mostly self-directed sessions. Echocardiograms taken near baseline, post-intervention, and post-maintenance visits were reviewed retrospectively. Diastolic dysfunction at baseline was defined by any of the following: E/A ratio > 2, mitral deceleration time < 160 ms, septal or lateral E/e' > 14, or tricuspid regurgitant jet velocity > 2.8 m/s. Atrial strain was measured using TOMTEC software. No significant improvements from baseline to post-intervention were observed in conventional diastolic function parameters or atrial strain, including patients with baseline diastolic dysfunction (n = 9). Among those with baseline diastolic dysfunction, there was a strong inverse correlation between the change in E/A ratio and the change in peak VO
Indexed as
Identifiers
41843013What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.