ArticleJournal of neurophysiology2026
Cellular properties and axonal projections of thyrotropin-releasing hormone-expressing neurons in the mouse lateral hypothalamic area.
Maggie A Khuu, Monica S Antony, Jeremy H Lesser, Kristen S Springer, Eneida M Wainman, Falyne C Driver, Daniel K Mulkey, Alexander C Jackson
Abstract read
In one paragraphArticle in Journal of neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Maggie A KhuuDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut, United States.
Monica S AntonyDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut, United States.
Jeremy H LesserDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut, United States.
Kristen S SpringerDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut, United States.
Eneida M WainmanDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut, United States.
Falyne C DriverDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut, United States.
Daniel K MulkeyDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut, United States.ORCID 0000-0002-7040-3927 Alexander C JacksonDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut, United States.ORCID 0000-0001-7489-3946 Funding
Glial chemosensitivity: pH sensing and interactions with neuronal chemoreceptorsR01HL104101 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI MULKEY, DANIEL K, OLSEN, MICHELLE L · 2010 to 2024
$5.5MInhibitory Cell Types and Circuits in the Lateral HypothalamusR01MH112739 · NIMH · UNIVERSITY OF CONNECTICUT STORRS · PI Alexander Choi Jackson · 2017 to 2026
$5.1MRole of KCNQ2 Channels in Control of BreathingR01HL137094 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI MULKEY, DANIEL K, TZINGOUNIS, ANASTASIOS · 2018 to 2025
$4.1MA novel trans-synaptic adhesion complex as a regulator of hypocretin/orexin control of arousalR01NS131664 · NINDS · UNIVERSITY OF CONNECTICUT STORRS · PI Alexander Choi Jackson, David Christopher Martinelli · 2024 to 2026
$1.9MMolecular signature of parafacial expiratory neuronsR21NS134132 · NINDS · UNIVERSITY OF CONNECTICUT STORRS · PI MULKEY, DANIEL K · 2023 to 2023
$443kIdentification of chemosensitive cells within the lateral hypothalamusF31HL160191 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI KHUU, MAGGIE ANN · 2021 to 2024
$173kHHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL104101HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL137094HHS | NIH | National Institute of Mental Health (NIMH) R01MH112739HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS131664HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R21NS134132NHLBI NIH HHS F31 HL160191NIMH NIH HHS R01 MH112739NINDS NIH HHS R01 NS131664
6 · The paper itselfAbstract
The lateral hypothalamic area (LHA) is well-known for its conserved role in modulating and driving many forms of innate behaviors, yet the cellular diversity underlying these functions remains incompletely understood. Although neurons expressing the neuropeptide thyrotropin-releasing hormone (TRH) in the hypothalamic paraventricular nucleus have been well-characterized for their hypophysiotropic functions and role in metabolism and feeding behavior, other hypothalamic TRH-expressing neurons, such as those located in the LHA, have received comparatively little attention. Here, using a viral-targeting approach in a
Indexed as
AxonsHypothalamic Area, LateralNeuronsThyrotropin-Releasing HormoneAction PotentialsAnimalsFemaleMaleMiceMice, Inbred C57BLMice, TransgenicThyrotropin-Releasing Hormoneburst firinghypothalamic circuitshypothalamuslateral hypothalamic areathyrotropin-releasing hormone
Identifiers
PMID41843451
PMCPMC13143218
What Socratic holds
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