ArticlePloS one2026
Distribution and evolution of the LysR-type transcriptional regulators of the Salmonella genus.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
LysR-type transcriptional regulators (LTTRs) are one of the most abundant transcriptional regulators in nature and are involved in multiple essential biological process in bacteria. In this work we show that LTTRs are highly abundant in Salmonella enterica subspecies enterica serovars able to infect humans (S. Typhi), whereas the number of LTTRs decreases substantially in reptile commensals (Salmonella enterica subspecies arizonae, diarizonae, houtenae, indica, salamae and Salmonella bongori). In addition, it is also reported the presence of a Salmonella LTTR core, LTTRs exclusive to the Salmonella genus and LTTRs like CysB that is widely distributed in the Enterobacteriales order and their orthologous sequences separate clades at the genus level, suggesting that CysB has evolved in parallel with the corresponding lineage. Therefore, there are LTTRs that evolved as part of the core of microorganisms that provide essential genetic functions to the cell, as well as a LTTR accessory pool that provides different capabilities to specific microorganisms for survival in nature and in different environments of the host.
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Registered trials
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