Evidence map›Paper›PMID 41845158›Full record

ReviewDiscover nano2026

Integration of nanotechnology in triple negative breast cancer research: a bibliometric and emerging trends analysis.

Israel Ogwuche Ogra, Faustina Ntim Opoku, Jeremiah Zaphnathpaaneah Adaji, Samson Usman, Daniel Thakuma Tizhe, Shadrack Dangabar Apollos, Eneh Philip, Emohchonne Utos Jonathan, Kodjovi Sossou, Wadzani Palnam Dauda

Abstract readReview
In one paragraph

Review in Discover nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Israel Ogwuche OgraBiological Institute, Tomsk State University, Tomsk, Russian Federation, 634050. ograisrael@gmail.com.ORCID http://orcid.org/0000-0002-7121-0713
Faustina Ntim OpokuTomsk Polytechnic University, Tomsk, Russian Federation.ORCID http://orcid.org/0009-0008-1256-1928
Jeremiah Zaphnathpaaneah AdajiSchool of Health Sciences, Maduka University, Ekwegbe-Nsukka, Enugu State, Nigeria.ORCID http://orcid.org/0000-0002-8607-7927
Samson UsmanDepartment of Crop Protection, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.ORCID http://orcid.org/0009-0008-6838-8378
Daniel Thakuma TizheAdamawa State Post Primary Schools Management Board, P.M.B. 2260, Yola, 640230, Nigeria.ORCID http://orcid.org/0000-0002-2661-0603
Shadrack Dangabar ApollosDepartment of Biochemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.ORCID http://orcid.org/0009-0005-3915-8811
Eneh PhilipUNESCO International Centre for Biotechnology, Nsukka, 410001, Enugu State, Nigeria.ORCID http://orcid.org/0009-0007-4920-4783
Emohchonne Utos JonathanDepartment of Biochemistry, Federal University Wukari, Wukari, 670102, Taraba State, Nigeria.ORCID http://orcid.org/0000-0002-8576-8910
Kodjovi SossouLaSBASE: Laboratoire des Sciences Biomédicales, Alimentaires et de Santé Environnementale, Lome, Togo. skodjovi.fr@gmail.com.ORCID http://orcid.org/0000-0003-2321-0644
Wadzani Palnam DaudaDepartment of Agronomy, Federal University, Gashua, Yobe State, Nigeria.ORCID http://orcid.org/0000-0002-5233-0058

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTriple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with a receptor-negative profile and poor prognosis. It mostly affects young African-American, Hispanic women, and BRCA 1 mutation carriers. Nanotechnology, with its capacity to manipulate materials at the nanoscale, offers promising avenues for enhancing therapeutic delivery, imaging, and biomarker detection for better treatment outcomes in TNBC. The purpose of this study was to explore the intellectual landscape, identify key contributors and emerging trends, and predict future research directions in the application of nanotechnology for triple-negative breast cancer (TNBC) research.

methodThe Bibliometrix R package and VOSviewer were used to analyze 405 documents indexed in the Scopus database from 2013 to 2025.

resultsAn annual growth rate of 22.79% was observed, indicating increasing interest in this field. China was the leading country in this field, with Huazhong University of Science and Technology and Zhang Y as the most relevant institution and the most prolific author. Notably, the top 10 most relevant institutions were based in China. The International Journal of Nanomedicine and the Journal of Controlled Release had the highest number of publications, but the latter was the most impactful journal. Emerging trends identified included ferroptosis, immunotherapy, immunogenic cell death, tumor microenvironment, and RNA nanotechnology.

conclusionFurther research into ferroptosis-based therapy for TNBC, immunogenic cell death (ICD) with nano-enabled immunotherapy, multimodal nanotheranostics for TNBC, and clinical translation of NT in TNBC studies is recommended to advance nanotechnology research in TNBC.

Indexed as

BibliometricsEmerging trendsNanotechnologyScopusTriple-negative breast cancer

Identifiers

PMID41845158
PMCPMC12996511

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.