Evidence mapPaperPMID 41845458Full record

ReviewChinese medicine2026

Regulatory mechanisms of Traditional Chinese Medicine on gut microbiota in diabetic microvascular complications.

Yiyang Peng, Chenyao Sun, Zheng Wang, Xiaohui Fan

Abstract readReview
In one paragraph

Review in Chinese medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yiyang PengCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.
Chenyao SunCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.
Zheng WangCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. wangzheng89@zju.edu.cn.
Xiaohui FanCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. fanxh@zju.edu.cn.

Funding

Breakthrough plan project of Innovation Center of Yangtze River Delta, Zhejiang University 2023GJJH002 X.F.Central Government Guiding Local Science and Technology Development Funds 2025ZY01023"Pioneer" and "Leading Goose" R&D Program of Zhejiang 2024C03106 X.F.
6 · The paper itself

Abstract

Diabetic microvascular complications are the most common and serious late-stage problems with diabetes patient, while existing antidiabetic treatments still have limited effects in preventing or reversing microvascular damage. Traditional Chinese Medicine (TCM) has been applied in clinical practice for centuries, showing excellent therapeutic effects in alleviating diabetic microvascular complications. Recently, the regulatory effects of gut microbiota, especially concepts such as the "gut-retina axis" and "gut-kidney axis" have been proposed and supported by accumulating experiment, which shows the importance of gut microbiota in microvascular injury. This review focuses on how TCM-gut microbiota interactions contribute to the prevention and treatment of diabetic microvascular complications, reviewing and organizing the latest evidence from experimental and clinical research. We further summarize current limitations in the field and discuss future direction to better uncover the mechanisms of TCM-microbiota interactions.

Indexed as

Diabetic microvascular complicationsGut microbiotaTraditional Chinese Medicine

Identifiers

PMID41845458
PMCPMC12997932

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.