Evidence map›Paper›PMID 41846957›Full record

ArticlebioRxiv : the preprint server for biology2026

Organization and evolution of sex-biased gene expression in

Dawn S Chen, Helena Gifford, Yerbol Z Kurmangaliyev, Yun Ding

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dawn S ChenDepartment of Biology, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-0198-2216
Helena GiffordDepartment of Biology, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0009-0002-5616-8710
Yerbol Z KurmangaliyevDepartment of Biology, Brandeis University, Waltham, MA 02453, USA.ORCID 0000-0003-4829-2025
Yun DingDepartment of Biology, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-8915-8434

Funding

From association to causation: pinpointing the genetic and molecular determinants underlying natural behavioral variationsR35GM142678 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DING, YUN · 2021 to 2025
$2.2M
NIGMS NIH HHS R35 GM142678
6 · The paper itself

Abstract

Sexually dimorphic behaviors are widespread across animals. A key open question is how the underlying sexual circuits, which encode these behaviors, evolve to meet sex-specific fitness needs despite being built from largely shared developmental blueprints. Here, we use single-cell transcriptomics, leveraging the sex determination gene

Identifiers

PMID41846957
PMCPMC12991140

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.