Evidence mapPaperPMID 41847188Full record

ArticleChinese journal of cancer research = Chung-kuo yen cheng yen chiu2026

Frontiers in bacterial outer membrane vesicles: From basic characteristics to cancer therapy.

Siyang Ma, Jianxuan Sun, Jingyu Xu, Ye An, Jinzhou Xu, Shaogang Wang, Qidong Xia

Abstract read
In one paragraph

Article in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Siyang Ma *Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Jianxuan Sun *Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Jingyu XuDepartment and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Ye AnDepartment and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Jinzhou XuDepartment and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Shaogang WangDepartment and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Qidong XiaDepartment and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial outer membrane vesicles (OMVs) are spherical nanostructures that originate from Gram-negative bacteria. They are gaining attention as powerful tools in cancer diagnostics and therapy due to their unique biological properties. These vesicles, which range from 50 to 250 nm in size, carry molecular components from their parent bacteria, allowing them to play important roles in bacterial defense and microbial ecosystems. Their lipid bilayer structure facilitates targeted drug delivery, while their natural immunogenic properties hold promise for cancer immunotherapy by helping overcome immune evasion in the tumor microenvironment. Moreover, OMVs have potential as biomarkers in liquid biopsies, particularly for cancers associated with bacteria, such as gastric and colorectal cancers. Their ability to interact with the intratumoral microbiota further indicates their relevance in tumor pathogenesis. This review aims to provide a comprehensive overview of the fundamental biology of OMVs and their emerging applications in cancer therapy.

Indexed as

bacteriabiologycancerextracellular vesiclesOuter membrane vesicles

Identifiers

PMID41847188
PMCPMC12989309

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.