ArticleFrontiers in veterinary science2026
High-grain diet-induced ruminal acidosis triggers systemic inflammation and serum metabolic reprogramming in dairy cows.
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
High-grain diets are widely used to meet the energy demands of high-producing dairy cows; however, excessive grain intake predisposes cows to ruminal acidosis and subsequent systemic inflammation, compromising health and productivity. This study aimed to characterize systemic inflammatory responses and associated serum metabolic alterations induced by high-grain feeding. Fourteen mid-lactation dairy cows fitted with permanent rumen fistulas were subjected to a gradual increase in dietary corn grain to induce ruminal acidosis. Blood samples were collected under normal and acidosis conditions; inflammatory biomarkers were quantified using enzyme-linked immunosorbent assay (ELISA), and serum metabolomic profiles were analyzed by gas chromatography-time of flight mass spectrometry
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