Evidence mapPaperPMID 41848883Full record

ReviewArchives of microbiology2026

Nanoformulations of essential oils for the treatment of fungal diseases, with a focus on dermatophytes.

Ghulam Muhayyudin Chattha, Yasmin Louise Ramos de Andrades Cappellari, Walter Orlando Beys-da-Silva, Luiza Abrahão Frank, Lucélia Santi

Abstract readReview
In one paragraph

Review in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ghulam Muhayyudin ChatthaFaculty of Pharmacy, Federal University of Rio Grande do Sul, Porto Alegre, Brazil. gmchattha234@gmail.com.
Yasmin Louise Ramos de Andrades CappellariFaculty of Pharmacy, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Walter Orlando Beys-da-SilvaFaculty of Pharmacy, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Luiza Abrahão FrankFaculty of Pharmacy, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Lucélia SantiFaculty of Pharmacy, Federal University of Rio Grande do Sul, Porto Alegre, Brazil. lucelia.santi@ufrgs.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal infections, particularly those caused by dermatophytes, affect over 25% of the world's population and pose a significant public health risk to both humans and animals. Conventional antifungal treatments face substantial challenges like drug resistance, adverse effects, and require long-term systemic medications. Essential oils (EOs) have attracted attention for their antimicrobial properties; however, their therapeutic applications have been hampered by their low solubility and rapid degradation. Nanotechnology addresses these limitations by encapsulating EOs to enhance their durability, bioavailability, and antifungal properties. This review covers the potential EO-based nanoformulations for treating fungal infections, with a focus on dermatophytes. It also highlights how nanoencapsulation may help reduce drug resistance, toxicity, and adverse effects. However, there are some limitations. The effectiveness of treating fungal infection can vary depending on the EO's composition, fungal species, and how the nanoformulation is formulated. Future research should emphasize standardizing formulation protocol and evaluating in vivo efficacy and safety through well-designed clinical trials. While EOs represent a promising approach, they are not a substitute for evidence-based antifungal treatment and must not be used without medical guidance.

Indexed as

Antifungal AgentsArthrodermataceaeDermatomycosesOils, VolatileAnimalsDrug CompoundingDrug Resistance, FungalHumansNanotechnologyAntifungal AgentsOils, VolatileAntifungal agentsAntifungal drug resistanceDermatomycosesDermatophytosisNanotechnologyNatural products

Identifiers

PMID41848883
PMCPMC12999649

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.