ArticleNeuroinformatics2026
Global Research Trends, Hotspots and Collaborative Networks in Brain-Derived Extracellular Vesicles: A Multi-Database Bibliometric Analysis.
Article in Neuroinformatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Brain-derived extracellular vesicles (bdEVs) are emerging mediators of intercellular communication with increasing significance in neuroscience and translational medicine. We conducted a cross-database bibliometric analysis of PubMed, Scopus, and Web of Science (2000–June 2025) to map global research trends, hotspots, and collaboration networks in bdEV research. After multi-stage deduplication and screening, the remaining original research articles were included for quantitative and network analyses. Publication output rose sharply after 2018 and peaked in 2024, reflecting rapid field expansion. The United States and China were the most productive contributors, with recent leadership shifting toward China with international collaboration intensifying, particularly through US–China partnerships. A compact author core and leading institutions such as Johns Hopkins University and the University of California drive the field, while the Journal of Extracellular Vesicles and several multidisciplinary and clinical journals serve as primary outlets. Keyword and cluster analyses revealed dominant themes such as extracellular vesicles/exosomes, astrocytes, neuroinflammation, biomarkers, and neurodegenerative disease alongside emerging foci in cell-type–specific bdEV biology, multi-omics profiling, and translational biomarker development. Funding is led by the NIH, European Union, and National Natural Science Foundation of China. Overall, bdEV research has matured into a globally networked, interdisciplinary domain with increasing translational potential. Future priorities include methodological harmonization, expanded international collaboration, and targeted efforts to validate bdEV biomarkers and therapeutic applications.
Indexed as
Identifiers
41848985What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.