Evidence map›Paper›PMID 41850399›Full record

ArticleThe Journal of biological chemistry2026

d-lactate drives lysine d-lactylation to regulate metabolism in Escherichia coli.

Jianji Zhang, Yong Zang, Zhiqing Yu, Fei Zhao, Jingya Wu, Yuhan Wang, Aiyuan Wang, Guijin Zhai, Yanpu Han, Chen Chen and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Lactate Signal: Modulator of Cellular Energy Production and Anabolism.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Lactate-Mediated Lysine Lactylation in Renal Fibrosis: Current Progress and Challenges.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jianji ZhangKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China; Department of General Surgery, Longgang Central Hospital of Shenzhen, Shenzhen, China.
Yong ZangKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Zhiqing YuKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Fei ZhaoKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Jingya WuKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Yuhan WangKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Aiyuan WangKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Guijin ZhaiKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Yanpu HanKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Chen ChenKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Jinjun YeDepartment of General Surgery, Longgang Central Hospital of Shenzhen, Shenzhen, China.
Hanyang DongKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. Electronic address: donghanyang@tmu.edu.cn.
Kai ZhangKey Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Institute of Immunology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China; Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China. Electronic address: kzhang@tmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

l-lactate-derived lysine l-lactylation (K

Indexed as

Escherichia coliLactic AcidLysineCoenzyme A-TransferasesEscherichia coli ProteinsProtein Processing, Post-TranslationalSirtuinscobB protein, E ColiCoenzyme A-TransferasesEscherichia coli ProteinsLactic AcidLysineSirtuinsbacterialysine d-lactylationmetabolismpost-translational modificationsproteomics

Identifiers

PMID41850399
PMCPMC13090971

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.