Observational studyFamily medicine and community health2026
Transition time between long-term conditions among childbearing women in England: a nationwide observational analysis.
Observational study in Family medicine and community health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.Family medicine and community health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine transition times between long-term conditions (LTCs) and their associated determinants among childbearing women.
designA population-based cohort study. We estimated median times to progress from 1 to 2, 2 to 3, 3 to 4 and 4 to ≥5 LTCs, stratified by ethnicity, socioeconomic status and region. 10-year risks of progression from first to second LTC were estimated by entry cohort (pre-2013 vs ≥2013) using Kaplan-Meier methods, with determinants assessed using Weibull survival models.
settingEnglish primary care records (CPRD Aurum and GOLD) and pregnancy registers.
participantsA total of 2 160 157 women with a first LTC diagnosis during reproductive years (ages 15-49) and at least one recorded pregnancy between 2003 and 2022.
resultsApproximately 65% with one LTC progressed to develop two or more LTCs. The median time to develop additional LTCs decreased progressively: 5.58 years (from 1 to 2), 4.45 years (from 2 to 3), 3.89 years (from 3 to 4) and 3.68 years (from 4 to 5+). Women diagnosed with their first LTC from 2013 onwards transitioned to second LTC faster than those diagnosed before 2013 (χ² = 4260.55, p<0.001). Faster progression was observed among women from the most deprived backgrounds compared with the least deprived (TR 0.79, 95% CI 0.79 to 0.80). Compared with Southwest England, women in the Northwest, West Midlands and Southeast acquired additional LTCs more rapidly. Ethnic variations in the risk of progression were also observed in specific contexts. Furthermore, analysis of baseline condition-specific trajectories showed that women with an initial diagnosis of cardiomyopathy experienced the fastest transition to a subsequent LTC (median survival time (MST) 3.89 years; 95% CI 0.99 to 11.78). This was followed by women with coronary heart disease (MST 4.21 years; 95% CI 1.30 to 11.34), diabetes (MST 4.25 years; 95% CI 1.39 to 9.20) and anxiety (MST 4.29 years; 95% CI 1.46 to 10.12).
conclusionLTC accumulation among childbearing women is driven by socioeconomic deprivation, ethnicity and regional disparities. Targeted interventions for high-risk groups, alongside efforts to address structural inequalities, may help slow this progression.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.