Evidence map›Paper›PMID 41851774›Full record

ArticleBMC chemistry2026

Comprehensive experimental and theoretical investigations of novel triazine Schiff base metal complexes: spectroscopic, electrochemical, DNA interaction, in vitro cytotoxicity, antimicrobial, and in silico studies.

Gehad Abd El-Hakeem, Gamal A Gouda, Khaled A Abd El-Rahem, Shimaa Hosny

Abstract read
In one paragraph

Article in BMC chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gehad Abd El-HakeemDepartment of Chemistry, Faculty of Science, Assiut Branch, Al-Azhar University, Assiut, 71524, Egypt.
Gamal A GoudaDepartment of Chemistry, Faculty of Science, Assiut Branch, Al-Azhar University, Assiut, 71524, Egypt. ggouda73@azhar.edu.eg.
Khaled A Abd El-RahemDepartment of Chemistry, Faculty of Science, Assiut Branch, Al-Azhar University, Assiut, 71524, Egypt.
Shimaa HosnyDepartment of Chemistry, Faculty of Science, New Valley University, Alkharga, 72511, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing resistance of bacteria and cancer to present treatments is a clinical and laboratory concern. In this study, a novel Schiff base ligand (HL) was synthesized in this work through a solvent-free method, involving the reaction of 2,4-diamino-6-phenyl-1,3,5-triazine with 2-hydroxy-1-naphthaldehyde under mild and eco-friendly conditions. The Ni(II) and Zn(II) complexes were then synthesized and confirmed by different spectroscopic and analytical methods. The results suggest that both complexes have an octahedral geometry, in good agreement with the computational findings. The binding mood of these compounds with CT-DNA was examined using cyclic voltammetry and UV-vis spectroscopy, which revealed a partial intercalation mode. The findings demonstrated strong DNA-binding affinity with binding constants (K

Indexed as

antimicrobial activityComputationalcyclic voltammetryCytotoxicityDNA interactionSchiff base

Identifiers

PMID41851774
PMCPMC13064358

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.