Evidence map›Paper›PMID 41851996›Full record

Observational studyRenal failure2026

Effect of intravitreal bevacizumab on kidney function and proteinuria among diabetic patients: a prospective observational study in Asian population.

Brajesh Mourya, Sukhwinder Singh Sangha, Asheesh Kumar, Timitrov P, Raj Kanwar Yadav, Dipankar Bhowmik, Sanjay Kumar Agarwal, Rajesh Sinha, Shorya Vardhan Azad

Abstract readObservational Study
In one paragraph

Observational study in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brajesh MouryaDepartment of Nephrology, AIIMS, New Delhi, India.
Sukhwinder Singh SanghaDepartment of Nephrology, Command Hospital Chandimandir, Panchkula, India.ORCID 0000-0003-2805-2323
Asheesh KumarDepartment of Nephrology, AIIMS Vijaypur, Jammu, India.ORCID 0000-0003-2513-3902
Timitrov PDepartment of Nephrology, AIIMS, Mangalagiri, Andhra Pradesh, India.ORCID 0009-0004-4990-1632
Raj Kanwar YadavDepartment of Nephrology, AIIMS, New Delhi, India.
Dipankar BhowmikDepartment of Nephrology, AIIMS, New Delhi, India.
Sanjay Kumar AgarwalDepartment of Nephrology, AIIMS, New Delhi, India.
Rajesh SinhaAll India Institute of Medical Sciences, Dr Rajendra Prasad Centre for Ophthalmic Sciences, New Delhi, India.
Shorya Vardhan AzadAll India Institute of Medical Sciences, Dr Rajendra Prasad Centre for Ophthalmic Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many studies have investigated the ocular benefits of intravitreal bevacizumab but there is scarcity of literature evaluating the effects of bevacizumab on kidney function and proteinuria especially in the Asian population. This study aims to investigate the effect of intravitreal injection of bevacizumab on proteinuria and kidney function in patients with diabetic retinopathy. This prospective observational study included 50 patients with diabetes and proliferative diabetic retinopathy (PDR) and/or significant diabetic macular edema, who have received intravitreal bevacizumab injection at a tertiary care center in India. Changes in the urinary albumin-to-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) at one month and six months after injection were measured. This study reported no significant change in eGFR and UACR at one month (

Indexed as

Angiogenesis InhibitorsBevacizumabDiabetic NephropathiesDiabetic RetinopathyMacular EdemaProteinuriaAdultAgedAlbuminuriaCreatinineFemaleGlomerular Filtration RateHumansIndiaIntravitreal InjectionsKidneyAngiogenesis InhibitorsBevacizumabCreatinineanti-vascular endothelial growth factordiabetic retinopathyIntra vitreal bevacizumabkidney dysfunctionproteinuria

Identifiers

PMID41851996
PMCPMC13003856

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.