Evidence map›Paper›PMID 41852680›Full record

ArticleFrontiers in nutrition2026

Unraveling the volatile profile and bioactivity of Zhoupigan (

Huanhuan Xu, Jialiang Zou, Xuelian Gan, Fu Wang, Lin Chen, Hongping Chen, Yuan Hu, Youping Liu

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Food science & nutrition · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huanhuan XuSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jialiang ZouSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xuelian GanSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Fu WangSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Lin ChenSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Hongping ChenSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yuan HuSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Youping LiuSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Zhoupigan ( Methods: In this study, ZJPEO was extracted by steam distillation (SD) and supercritical fluid extraction (SFE) and analyzed using FTIR, E-nose, HS-GC-IMS and HS-SPME-GC-MS. And its antioxidant and antimicrobial activities were evaluated Results: FTIR and E-nose revealed clear compositional differences between steam-distilled essential oil (SDEO) and supercritical fluid-extracted essential oil (SFEO). HS-GC-IMS detected 63 VOCs and, based on VIP > 1, identified five marker compounds. HS-SPME-GC-MS identified 1,250 VOCs, showing terpenoids and esters as major contributors to aroma and bioactivity. KEGG enrichment highlighted sesquiterpene and triterpene biosynthesis as key pathways. Flavor wheel analysis indicated that SFEO had stronger sweet, green, and woody notes and exhibited potent antioxidant and antimicrobial activities associated with specific VOCs. Discussion: Overall, this work supports optimizing ZJPEO extraction and promoting its value-added, sustainable utilization.

Indexed as

BioactivityEssential oilsHS-GC-IMSHS-SPME-GC-MSZhoupigan (Citrus reticulata cv. Manau Gan)

Identifiers

PMID41852680
PMCPMC12992264

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.