Evidence map›Paper›PMID 41852807›Full record

ArticleGlobal epidemiology2026

Effect of completing eight or more antenatal care contacts on adverse pregnancy outcomes in a district hospital in Ghana: A propensity score-matched and doubly robust analysis.

Frederick Osei Owusu, Emmanuel Konadu, Helena Addai-Manu, Julius Kwabena Karikari, Esther Serwah Agbedinu, Nuheila Ibrahim, Lydia Asenso, Mercy Addae, Joseph Osarfo, Bernice Enyonam Akpaloo and 2 more

Abstract read
In one paragraph

Article in Global epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Frederick Osei OwusuJuaben Government Hospital, Juaben, Ghana.
Emmanuel KonaduUniversity Hospital, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Helena Addai-ManuJuaben Government Hospital, Juaben, Ghana.
Julius Kwabena KarikariUniversity Hospital, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Esther Serwah AgbedinuJuaben Government Hospital, Juaben, Ghana.
Nuheila IbrahimUniversity Hospital, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Lydia AsensoJuaben Government Hospital, Juaben, Ghana.
Mercy AddaeUniversity Hospital, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Joseph OsarfoDepartment of Community Health, School of Medicine, University of Health and Allied Health Science, Ho, Ghana.
Bernice Enyonam AkpalooUniversity Hospital, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Mawuse KanfraSt. Dominic Catholic Hospital, Akwatia, Ghana.
Douglas Aninng OpokuUniversity Hospital, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Evidence from low- and middle-income countries (LMICs), especially using robust causal inference techniques to estimate the association between ≥8 antenatal care (ANC) contacts and adverse pregnancy outcomes, remains limited. This study examines the association between completing eight or more ANC contacts and adverse pregnancy outcomes, specifically low birth weight (LBW) and preterm birth (PTB). Methods: A cross-sectional study was conducted using retrospective delivery data at Juaben Government Hospital, Ghana. LBW and PTB were compared between women who made ≥8 ANC contacts and those who did not. Propensity score matching (1:1), inverse probability of treatment weighting, and doubly robust estimates were employed to address confounding and estimate the association between completing ≥8 ANC contacts and LBW and PTB. Results: At baseline, the sample included 2156 women, of whom over half (51.3%) had ≥8 ANC contacts before delivery. After matching, women in both groups had similar characteristics. After matching on covariates, women with ≥8 ANC contacts had approximately 31.0% (ATT: 0.69; 95%CI: 0.53-0.90) and 54.0% (ATT: 0.46; 95%CI: 0.37-0.57) lower risks of delivering a LBW infant and a PTB, respectively. Inverse probability of treatment weighting and doubly robust estimates yielded comparable estimates for both outcomes. In a secondary analysis of ≥4 ANC contacts, the magnitude of the association was weaker than that observed in the ≥8 ANC model. Conclusion: This study demonstrated that completing ≥8 ANC contacts was consistently associated with lower odds of LBW and PTB among this cohort of pregnant women. This finding adds to the limited empirical evidence from LMICs on the implementation of the WHO eight-contact ANC model, suggesting that higher ANC contacts in a similar resource-constrained setting may be associated with improved maternal and infant outcomes.

Indexed as

Antenatal careDoubly robustGhanaLow birth weightPreterm birthPropensity score matching

Identifiers

PMID41852807
PMCPMC12993169

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.