Evidence map›Paper›PMID 41852928›Full record

ArticleJournal of circulating biomarkers

Dysfunctional high-density lipoprotein predicts survival, renal recovery and the need for kidney replacement therapy in acute kidney injury.

Nikolaos Pagonas, Oliver Pfeifer, Stefan Erfurt, Meike Hoffmeister, Oliver Ritter, Theodoros Kelesidis, Daniel Patschan

Abstract read
In one paragraph

Article in Journal of circulating biomarkers. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nikolaos PagonasDepartment of Internal Medicine - Cardiology, Neuruppin University Hospital, Brandenburg Medical School (Theodor Fontane), Neuruppin - Germany.
Oliver PfeiferDepartment of Internal Medicine I - Cardiology, Nephrology and Intensive Care Medicine, Brandenburg University Hospital, Brandenburg Medical School (Theodor Fontane), Brandenburg an der Havel - Germany.ORCID https://orcid.org/0009-0005-3246-4170
Stefan ErfurtDepartment of Internal Medicine I - Cardiology, Nephrology and Intensive Care Medicine, Brandenburg University Hospital, Brandenburg Medical School (Theodor Fontane), Brandenburg an der Havel - Germany.ORCID https://orcid.org/0000-0001-8892-1805
Meike HoffmeisterFaculty of Health Sciences (FGW), joint faculty of the University of Potsdam, the Brandenburg Medical School Theodor Fontane and the Brandenburg Technical University Cottbus-Senftenberg, Cottbus - Germany.
Oliver RitterFaculty of Health Sciences (FGW), joint faculty of the University of Potsdam, the Brandenburg Medical School Theodor Fontane and the Brandenburg Technical University Cottbus-Senftenberg, Cottbus - Germany.
Theodoros KelesidisDepartment of Medicine, Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center, Dallas, Texas - USA.
Daniel PatschanFaculty of Health Sciences (FGW), joint faculty of the University of Potsdam, the Brandenburg Medical School Theodor Fontane and the Brandenburg Technical University Cottbus-Senftenberg, Cottbus - Germany.ORCID https://orcid.org/0000-0002-6914-5254

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: There is growing evidence that oxidative stress contributes not only to the pathophysiology of atherosclerosis but also to acute kidney injury (AKI). This study investigated the prognostic value of nHDL Methods: nHDL Results: Among 132 participants, 16.7% died in the hospital, 36.4% required KRT, and 31.1% had no restoration of kidney function. For all primary endpoints, nHDL Conclusions: Impaired antioxidant HDL function is closely associated with clinically relevant AKI outcomes. nHDL

Indexed as

Acute Kidney InjuryDysfunctional HDLHDLoxKidney replacement therapyOxidized HDLRenal recovery

Identifiers

PMID41852928
PMCPMC12994525

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.