Evidence map›Paper›PMID 41854565›Full record

ArticleJACC. Advances2026

Mechanisms Underlying Reduced Peak Oxygen Uptake in Older Long-Term Breast Cancer Survivors.

Stephen J Foulkes, Edith Pituskin, Thomas McMurtry, Rachel J Skow, Justin Grenier, Nathan Weeldreyer, Corey Tomczak, Deirdre O'Neill, Robert C Welsh, Richard B Thompson and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stephen J FoulkesIntegrated Cardiovascular Exercise Physiology and Rehabilitation Lab, Faculty of Nursing, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada; Heart, Exercise and Research Trials Lab, St Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.
Edith PituskinIntegrated Cardiovascular Exercise Physiology and Rehabilitation Lab, Faculty of Nursing, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Thomas McMurtryIntegrated Cardiovascular Exercise Physiology and Rehabilitation Lab, Faculty of Nursing, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Rachel J SkowIntegrated Cardiovascular Exercise Physiology and Rehabilitation Lab, Faculty of Nursing, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Justin GrenierDepartment of Radiology and Diagnostic Imaging, Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Nathan WeeldreyerIntegrated Cardiovascular Exercise Physiology and Rehabilitation Lab, Faculty of Nursing, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Corey TomczakIntegrative Cardiovascular Physiology Research Program, College of Kinesiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Deirdre O'NeillDivision of Cardiology, Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada; Hochgebirgsklinik Davos, Medicine Campus Davos, Davos, Switzerland.
Robert C WelshDivision of Cardiology, Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada; Hochgebirgsklinik Davos, Medicine Campus Davos, Davos, Switzerland.
Richard B ThompsonDepartment of Radiology and Diagnostic Imaging, Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Mark J HaykowskyIntegrated Cardiovascular Exercise Physiology and Rehabilitation Lab, Faculty of Nursing, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada; Division of Cardiology, Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada; Hochgebirgsklinik Davos, Medicine Campus Davos, Davos, Switzerland. Electronic address: mhaykows@ualberta.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiotoxic breast cancer therapy is associated with acute reductions in peak oxygen uptake (VO

objectivesWe evaluated VO

methodsParticipants underwent maximal cardiopulmonary exercise testing to quantify VO

resultsOlder BCS had lower VO

conclusionsCompared to CON, older, long-term BCS display lower VO

Indexed as

cardio-oncologycardiorespiratory fitnesscardiotoxicityexercise intolerancemagnetic resonance imaging

Identifiers

PMID41854565
PMCPMC13309329

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.