ArticlePoultry science2026
Integrated multi-omics implicates the gut microbiota and bilirubin in abdominal fat deposition in Huainan yellow chickens.
Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Huainan yellow chicken is prized for its meat quality, but excessive abdominal fat deposition hampers its production efficiency. To investigate the underlying mechanisms, we compared high-fat deposition (HFD) and low-fat deposition (LFD) chickens using lipid metabolomics and 16S rRNA sequencing. The HFD group exhibited significantly higher carcass weight and abdominal fat index. Concordantly, serum levels of total bilirubin, triglycerides, cholesterol, glucose, and very-low-density lipoprotein were elevated, alongside upregulated expression of hepatic lipogenic genes (FASN, PPARγ, and PPARα). Liver lipidomics identified 144 significantly altered metabolites. Ileal microbiota analysis revealed a substantial enrichment of Lactobacillus and reductions in Escherichia-Shigella and Candidatus_Arthromitus in HFD chickens. The integrated analysis revealed strong correlations between microbial abundance and lipid metabolites, suggesting that gut microbes, especially Lactobacillus, may influence bilirubin metabolism and enterohepatic circulation. Collectively, our findings implicate a synergistic interaction where the gut microbiota (especially Lactobacillus) may modulate bilirubin enterohepatic circulation and hepatic lipogenesis, regulating abdominal fat deposition in Huainan yellow chickens, providing a novel theoretical basis for modulating fat accumulation in poultry through microbial strategies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.