Evidence map›Paper›PMID 41856669›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2026

Metabolic Imaging and Molecular Signatures Reveal Metabolic Phenotypes in Recurrent Glioblastoma.

Elizabeth J Li, Adam Kraya, Pedro Costa-Pinheiro, Joshua Scheuermann, Anthony J Young, Erin Schubert, Mariam Aboian, Robert Doot, Jeffrey B Ware, Austin R Pantel and 11 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Molecular Brain Tumor Imaging Beyond [AJR. American journal of roentgenology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Elizabeth J LiDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Adam KrayaCenter for Data Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Pedro Costa-PinheiroDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania.
Joshua ScheuermannDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Anthony J YoungDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Erin SchubertDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Mariam AboianDepartment of Radiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Robert DootDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Jeffrey B WareDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Austin R PantelDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Zev A BinderDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania.
Phillip B StormCenter for Data Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Adam C ResnickCenter for Data Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Nduka M AmankulorDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania.
Donald M O'RourkeDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania.
Arati DesaiDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and.
MacLean P NasrallahDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Steven BremDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania.
Stephen J BagleyDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and.
David MankoffDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Ali NabavizadehDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania; ali.nabavizadeh@pennmedicine.upenn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent glioblastoma remains a clinical challenge because of metabolic heterogeneity and the difficulty in differentiating true progression from therapy-related changes.

Indexed as

Brain NeoplasmsGlioblastomaAdultAgedCarboxylic AcidsCyclobutanesFemaleGene Expression ProfilingHumansMagnetic Resonance ImagingMaleMiddle AgedPhenotypePositron-Emission TomographyProspective StudiesRecurrenceCarboxylic AcidsCyclobutanesfluciclovine F-18amino acid PETdynamic PETglioblastomametabolic profilingRNA sequencing

Identifiers

PMID41856669
PMCPMC13224916

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.