Evidence mapPaperPMID 41857434Full record

ReviewSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2026

Polyacetylenes as antibacterial, antibiofilm, and anti-quorum-sensing agents: Sources, chemistry, bioactivities, and

Reham M Samra, Fatma M Abdel Bar

Abstract readReview
In one paragraph

Review in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Reham M SamraDepartment of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.ORCID http://orcid.org/0000-0001-6517-9409
Fatma M Abdel BarDepartment of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, 11942, Al-Kharj, Saudi Arabia. f.abdelbar@psau.edu.sa.ORCID http://orcid.org/0000-0003-0823-4015

Funding

Deanship of Scientific Research, Prince Sattam bin Abdulaziz University PSAU/2025/03/36227
6 · The paper itself

Abstract

The rise of multidrug-resistant bacteria now poses significant challenges, rendering many conventional medicines ineffective and necessitating the search for new antimicrobial agents. Polyacetylenes, both natural and synthetic, possess diverse biological activities, with their remarkable antibacterial potential being particularly significant. This review offers an in-depth evaluation of the therapeutic roles of polyacetylenes as antibacterial, antibiofilm, and anti-quorum-sensing agents, summarizing the tested compounds, their natural sources, the assays employed, and the bacterial strains investigated. It also provides an overview of their biosynthesis, distribution, and pharmacokinetic properties, along with a comprehensive analysis of their chemical classification and

Indexed as

AntibiofilmAntibiotic resistanceAsteraceaePolyacetylenesQuorum-sensingSAR

Identifiers

PMID41857434
PMCPMC13003075

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.