Evidence map›Paper›PMID 41858424›Full record

ArticleNeuropsychiatric disease and treatment2026

Effect of Venlafaxine on Inflammatory Level in Patients with Depression.

Huan Zhang, Na Huang, Xinxin Ma, Yanan Liu

Abstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Huan ZhangDepartment of Psychiatry, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.ORCID 0009-0009-2488-2187
Na HuangCentral Laboratory, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.ORCID 0009-0007-6953-4659
Xinxin MaDepartment of Psychiatry, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.ORCID 0009-0007-0809-6296
Yanan LiuDepartment of Psychiatry, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.ORCID 0009-0000-9903-9367

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Venlafaxine is widely applied to treat depression. Herein, we further explore the effect of venlafaxine on inflammatory level in patients with depression. Methods: Retrospectively, the medical data of patients (from January 2020 to February 2023, following up for 1 year) with depression (n=134) and without depression (health group, n=63) were collected. According to different treatment methods, patients with depression were categorized into the venlafaxine group (n=71) and the fluoxetine group (n=63). After treatment 8 weeks and 1 year, the baseline characteristics, therapeutic effect, inflammatory level and adverse events were analyzed. Results: After treatment 8 weeks and 1 year, there were significant improvements about depression and inflammatory level in venlafaxine group and fluoxetine group ( Conclusion: In this study, venlafaxine use was associated with improvement in depressive symptoms and correlated with reduced levels of inflammatory markers in patients with depression.

Indexed as

depressionHamilton depression scale-17inflammatory leveltherapeutic effectvenlafaxine

Identifiers

PMID41858424
PMCPMC12998920

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.