Differential effects of non-selective and cardio-selective beta-blocker therapy on ECG parameters in long QT syndrome type 1.

Marina Rieder, Vanessa Christe, Saranda Nimani, Peter M Deissler, Rachel M A Ter Bekke, Katja E Odening

Abstract read

In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marina RiederTranslational Cardiology, Department of Cardiology and Institute of Physiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.

Vanessa ChristeTranslational Cardiology, Department of Cardiology and Institute of Physiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.

Saranda NimaniTranslational Cardiology, Department of Cardiology and Institute of Physiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.

Peter M DeisslerDepartment of Cardiology, Maastricht University Medical Center+, Maastricht, Netherlands (the).

Rachel M A Ter BekkeDepartment of Cardiology, Maastricht University Medical Center+, Maastricht, Netherlands (the).

Katja E OdeningTranslational Cardiology, Department of Cardiology and Institute of Physiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

•Non-selective β-blockers markedly reduce Tpeak/end in LQT1 patients.•Cardio-selective β-blockers show no consistent effect on Tpeak/end.•The nsBB effect persists after exercise, independent of heart rate.•Tpeak/end shortening indicates decreased global repolarization heterogeneity and reduced arrhythmic risk.•Tpeak/end may serve as a novel ECG marker for β-blocker efficacy in LQT1.

Identifiers

PMID41858555

DOI10.1016/j.ijcha.2026.101901

PMCPMC12996241

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.