ReviewInternational journal of nanomedicine2026
Potential Application of Plant-Derived Extracellular Vesicles in Treatment of Burn Wounds.
Review in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Burns are triggered by exposure of skin to heat sources, chemicals, electric currents, or radiation. Due to the cross-interaction of multiple factors, the healing mechanism of burns is complex. In recent years, plant-derived extracellular vesicles (P-EVs) have been found to possess characteristics such as anti-inflammatory, antioxidant, antibacterial, and promotion of angiogenic, owing to their rich content of proteins, nucleic acids, and secondary metabolites, which make P-EVs have great application prospects in the field of tissue regeneration. This article, based on the specificities of healing mechanisms of burn wounds compared to general wounds, systematically reviews the extraction techniques of P-EVs, their bioactive components, and the molecular mechanisms in repair of burn wounds. Moreover, P-EVs have certain advantages in biocompatibility and promoting cell proliferation for repair, providing innovative strategies for the treatment of burn wounds directly or as a complement for the existing therapeutics. However, their clinical application still faces challenges such as the lack of standardized extraction processes, unclear targeting mechanisms, and long-term safety assessment. Future research can combine multidisciplinary technologies to further optimize the extraction and targeting of P-EVs, promoting their translational application in regenerative medicine. This article aims to provide theoretical references for the basic research and clinical practice of P-EVs in repair of burn wounds and to envision their development prospects as a new treatment method for burn wounds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.