ArticleExperimental and therapeutic medicine2026
Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report.
Article in Experimental and therapeutic medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The present case report describes a 31-year-old male patient with isolated spinal vasculitis. The patient initially presented with right-hand numbness and weakness, which later extended to both lower limbs, causing gait instability. MRI scans performed after the symptoms had extended to both lower limbs revealed a cervical lesion with T1 hypointensity, T2 hyperintensity and heterogeneous enhancement, initially suspected to be a tumor. Histopathological analysis of the spinal cord biopsy specimen revealed lymphocytic infiltration surrounding the small vessels of spinal cord, supporting a diagnosis of primary isolated spinal vasculitis. The patient was treated with high-dose intravenous methylprednisolone for 9 days (500 mg for 3 days, 250 mg for 3 days and 120 mg for 3 days), resulting in pronounced clinical improvement on follow-up neurological examination and no recurrence at the 2-year follow-up without additional immunosuppressive therapy. The present case underscores the diagnostic challenge of distinguishing vasculitis from spinal tumors and highlights the uncertainty regarding long-term recurrence prevention strategies.
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