ArticleEuropean heart journal. Imaging methods and practice2026
Atrial FDG avidity is associated with reduced atrial strain and contractility independent of atrial fibrillation and cardiac sarcoidosis.
Article in European heart journal. Imaging methods and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Cardiac MRI-based strain analysis for the assessment of left atrial dysfunction in patients with atrial fibrillation.The international journal of cardiovascular imaging · 2026Article
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11 authors.
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Abstract
Aims: Atrial myopathy encompasses structural, functional, electrical, and metabolic changes in the atrial myocardium. While remodelling such as left atrial (LA) dilation and reduced strain are well documented, metabolic alterations remain underexplored. 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) provides a non-invasive tool to assess myocardial glucose metabolism. This study evaluates the relationship between atrial FDG avidity and LA remodelling in patients undergoing cardiac imaging for suspected cardiac sarcoidosis (CS). Methods and results: We studied 120 patients who underwent both cardiac MRI and FDG-PET/CT at the University of Washington Medical Center. LA structural volume index (LAVi) and functional emptying fraction (LAEF), average long-axis strain, and phasic strain indices were derived from cine MRI using feature tracking. Atrial FDG avidity was quantified by SUVmax and atrial target-to-background ratio (aTBR) from PET/CT. LA average long axis strain was 37.1 ± 34.0%, LAEF 47.6 ± 16.1%, and LAVi 36.0 ± 23.0%. Atrial avidity was 2.4 ± 0.7 SUV. LA strain negatively and mildy correlated with both SUVmax ( Conclusion: Increased atrial FDG avidity is independently associated with impaired strain and enlarged LA, highlighting a metabolic component of atrial myopathy that may precede clinical AF.
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