Evidence map›Paper›PMID 41858883›Full record

ArticleiScience2026

Obesity mediates the association of outdoor artificial light at night with type 2 diabetes mellitus.

Xiaotian Liu, Zhongao Ding, Yinghao Yuchi, Ruiying Li, Wei Liao, Xiaokang Dong, Wenqian Huo, Jian Hou, Hualiang Lin, Xin Liu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaotian LiuDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, P.R. China.
Zhongao DingDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, P.R. China.
Yinghao YuchiDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, P.R. China.
Ruiying LiDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, P.R. China.
Wei LiaoDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, P.R. China.
Xiaokang DongNHC Key Laboratory of Prevention and Treatment of Cerebrovascular Diseases, Zhengzhou, Henan, P.R. China.
Wenqian HuoDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, P.R. China.
Jian HouDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, P.R. China.
Hualiang LinDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, P.R. China.
Xin LiuSchool of Public Health and Emergency Management, Southern University of Science and Technology, Shenzhen, Guangdong, P.R. China.
Kai ZhangDepartment of Environmental Health Sciences, College of Integrated Health Sciences, University at Albany, Rensselaer, NY, USA.
Chongjian WangDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to explore the association of outdoor ALAN exposure with T2DM and the mediating effects of obesity in Chinese rural adults. A total of 38,108 participants were recruited from the Henan Rural Cohort. ALAN was positively associated with T2DM and FPG, and negatively associated with insulin, HOMA-IR, as well as HOMA-β, and the effect sizes of per-quartile increase in ALAN were 1.24(1.19, 1.28), 0.14(0.13, 0.16), -1.19(-1.24, -1.14), -0.22(-0.25, -0.20), and -27.30(-29.11, -25.48), respectively. The elderly, men, current smokers, individuals with lower education or income, or physical inactivity were more vulnerable to ALAN-related adverse health effects. The associations of ALAN with T2DM and glucose metabolism were mediated by WC, BMI, WHtR, WHR, VFI, and BFP, with estimated mediation proportions of 36.41%, 25.14%, 33.98%, 22.33%, 24.39%, and 25.85%, respectively, for T2DM. These findings emphasize the need for targeted public health interventions for reducing ALAN-related adverse health effects in rural areas.

Indexed as

Health sciences

Identifiers

PMID41858883
PMCPMC12999289

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.