Evidence map›Paper›PMID 41859166›Full record

ArticleFrontiers in medicine2026

Development and validation of a nomogram prediction model for cardiovascular comorbidities in COPD patients based on hypertension.

Zhaojun Chen, Huan Li, Yuli Cai, Xuliang Chen, Deyi Zhou, Yihuan Su, Chaofeng Lin, Liangde Li, Dongjie Huang, Riken Chen and 3 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zhaojun Chen *The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Huan Li *The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Yuli Cai *The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Xuliang Chen *The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Deyi ZhouThe Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Yihuan SuThe Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Chaofeng LinThe Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Liangde LiThe Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Dongjie HuangThe Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Riken ChenThe Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Xiaoling WuThe Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Zhenzhen ZhengThe Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Mingpeng XuThe Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to examine the association between hypertension and cardiovascular comorbidities in patients with chronic obstructive pulmonary disease (COPD) and to construct a nomogram for predicting the risk of cardiovascular comorbidities in this population. Methods: This retrospective study included 1,447 patients with chronic obstructive pulmonary disease (COPD) and no pre-existing cardiovascular disease (CVD) from January 2018 to February 2022 at the Second Affiliated Hospital of Guangdong Medical University, with follow-up extending until August 2025. Patients were randomly assigned to a training cohort ( Results: The predictors incorporated into the nomogram model were age, diabetes mellitus, hypertension, and edema. The nomogram demonstrated good discriminative performance, with an area under the receiver operating characteristic (ROC) curve (AUC) of 0.82 (95% CI: 0.78-0.85) in the training cohort, 0.82 (95% CI: 0.77-0.87) in the internal validation cohort, and 0.90 (95% CI: 0.87-0.93) in the external validation cohort. Conclusion: This study demonstrated that the nomogram shows good discriminative performance and can effectively estimate the risk of cardiovascular disease in patients with chronic obstructive pulmonary disease. Age, diabetes mellitus, hypertension, and edema were identified as independent predictors.

Indexed as

cardiovascular diseasechronic obstructive pulmonary diseasehypertensionnomogramrisk prediction

Identifiers

PMID41859166
PMCPMC12996086

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.