Evidence map›Paper›PMID 41859643›Full record

ArticleMaterials today. Bio2026

Iron overload disrupts lipid desaturation through SKN-1 signaling in

Zhaoyang Dong, Yuxin Liao, Hao Shi, Jia Zhang, Jiajie Lin, Qiong Liu, Shiqing Zhang, Xiuqin Fan, Bin Liu, Yunqing Wang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhaoyang DongGuangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.
Yuxin LiaoSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, China.
Hao ShiSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, China.
Jia ZhangSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, China.
Jiajie LinSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, China.
Qiong LiuSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, China.
Shiqing ZhangState Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou, Guangdong, 510632, China.
Xiuqin FanHangzhou Linping Hospital of Integrated Traditional Chinese and Western Medicine, Hangzhou, Zhejiang, 311100, China.
Bin LiuZhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China.
Yunqing WangHangzhou Linping Hospital of Integrated Traditional Chinese and Western Medicine, Hangzhou, Zhejiang, 311100, China.
Yantao ZhengZhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China.
Lei GaoGuangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of biomaterials is shifting from bioinert designs toward bioactive and responsive systems, as exemplified by ferroptosis-inducible immunomodulatory adjuvants. Although these platforms enable programmed immune responses, their metallic components introduce distinct risks. Degradation or wear releases free metal ions (

Indexed as

C. elegansIron overloadLipid metabolismLongevityOxidative stress

Identifiers

PMID41859643
PMCPMC12996938

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.