Evidence map›Paper›PMID 41859654›Full record

ArticleJVS-vascular science2026

In vitro characterization and angiogenic potential of quality-and-quantity mononuclear cell-derived extracellular vesicles.

Suttipong Tianwattanatada, Nuttapol Chruewkamlow, Narinee Srimark, Ladawan Khowawisetsut, Kovit Pattanapanyasat, Chutipon Sathan-Ard, Pisol Senawongse, Nuttawut Sermsathanasawadi

Abstract read
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In one paragraph

Article in JVS-vascular science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Suttipong TianwattanatadaDepartment of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Nuttapol ChruewkamlowResearch Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Narinee SrimarkCenter of Excellence for Microparticle and Exosome in Diseases, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Ladawan KhowawisetsutCenter of Excellence for Microparticle and Exosome in Diseases, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kovit PattanapanyasatCenter of Excellence for Microparticle and Exosome in Diseases, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Chutipon Sathan-ArdResearch Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Pisol SenawongseFaculty of Dentistry, Mahidol University, Bangkok, Thailand.
Nuttawut SermsathanasawadiDepartment of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study evaluated the presence, production rate, and in vitro angiogenic properties of quality-and-quantity culture mononuclear cells-derived extracellular vesicles (QQMNC-EVs). Methods: Peripheral blood from three healthy volunteers was processed into five groups: QQMNC-EVs, QQMNCs, peripheral blood mononuclear cell-derived EVs (PBMNC-EVs), CD34 Results: QQMNC-EVs were identified and met established EVs criteria. QQMNCs produced the highest EVs yield. This was significantly higher than CD34 Conclusions: QQMNC-EVs were successfully identified and showed in vitro angiogenic efficacy, highlighting their potential as a novel therapeutic strategy for patients with no-option chronic limb-threatening ischemia. Clinical Relevance: Extracellular vesicles (EVs) were successfully identified and characterized from QQMNCs and had the highest production rate among the four cell groups: QQMNCs, standard peripheral blood mononuclear cells, CD34

Indexed as

AngiogenesisExtracellular vesiclesPeripheral blood mononuclear cellsProduction rateQuality-and-quantity culture media

Identifiers

PMID41859654
PMCPMC12995861

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.