ArticleJournal of the American Heart Association2026
Sex-Based Differences in Outcomes Following Mitral Valve Surgery: A Contemporary Analysis From 2 Institutions.
Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundDespite differences in operative characteristics in patients with mitral valve disease, it remains unclear if sex is an independent risk factor associated with perioperative mortality after mitral valve surgery.
methodsWe performed a retrospective cohort study of 3313 adult patients who underwent mitral valve surgery between 2011 and 2024 at 2 academic institutions. Patients were stratified by sex, and the primary outcome was operative mortality. Multivariable logistic regression was used to identify independent predictors of operative mortality.
resultsIn our cohort, 44.5% were women. Women were older (63.9 versus 62.2 years,
conclusionsDespite differences in baseline characteristics and surgical approach, operative mortality did not differ significantly by sex. Female sex was not significantly associated with operative mortality after adjustment for clinical and operative factors in patients undergoing elective mitral valve surgery.
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