Evidence mapPaperPMID 41860671Full record

ReviewMolecular biology reports2026

Anticancer properties of Artemisia species: mechanisms and experimental evidence.

Abdulmunem M Abulayha, Eman Eshawesh, Esam Alshareef, Fawzi Ebrahim, Adam Elzagheid

Abstract readReview
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In one paragraph

Review in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abdulmunem M AbulayhaLibyan Biotechnology Research Center, Department of Human Cells and Tissues. Tripoli, P.O. Box 30313, Tripoli, Libya. abdulmunem09@hotmail.com.
Eman Eshawesh
Esam Alshareef
Fawzi Ebrahim
Adam Elzagheid

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genus Artemisia (family Asteraceae) is widely recognized for its medicinal properties, among which artemisinin is the most notable, historically serving as a key antimalarial agent. Accumulating evidence now highlights the significant anticancer potential of Artemisia species, with bioactive compounds such as artemisinin and its derivatives exhibiting promising activity across multiple cancer types. This review provides a comprehensive overview of the molecular mechanisms underlying the anticancer effects of Artemisia-derived compounds, including apoptosis induction, cell cycle arrest, and oxidative stress modulation. In addition, it examines their therapeutic efficacy in preclinical in vivo models and summarizes findings from early-phase clinical trials. Despite encouraging preclinical results, challenges such as drug resistance, limited bioavailability, and barriers to clinical translation remain.

Indexed as

Antineoplastic Agents, PhytogenicArtemisiaNeoplasmsPlant ExtractsAnimalsAntineoplastic AgentsApoptosisArtemisininsCell Cycle CheckpointsHumansOxidative StressAntineoplastic AgentsAntineoplastic Agents, PhytogenicArtemisininsPlant ExtractsAnticancerApoptosisArtemisiaBioactive compoundsROS

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.