Evidence map›Paper›PMID 41865200›Full record

ArticleBiological trace element research2026

Arsenic Promotes Intracellular Aβ

Naphada Leelaprachakul, Daranee Visitnonthachai, Apichaya Niyomchan, Kanjanamas Maliphol, Piyajit Watcharasit, Jutamaad Satayavivad

Abstract read
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In one paragraph

Article in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Naphada LeelaprachakulLaboratory of Pharmacology, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Rd, Bangkok, 10210, Thailand.
Daranee VisitnonthachaiLaboratory of Pharmacology, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Rd, Bangkok, 10210, Thailand.
Apichaya NiyomchanDepartment of Anatomy, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Kanjanamas MalipholLaboratory of Pharmacology, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Rd, Bangkok, 10210, Thailand.
Piyajit WatcharasitLaboratory of Pharmacology, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Rd, Bangkok, 10210, Thailand. piyajit@cri.or.th.
Jutamaad SatayavivadLaboratory of Pharmacology, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Rd, Bangkok, 10210, Thailand.

Funding

Thailand Science Research and Innovation (TSRI) Grant no. 49892/4778750The Royal Golden Jubilee Ph.D. Program PHD/0207/2559
6 · The paper itself

Abstract

Arsenic exposure is associated with Alzheimer's disease (AD) development through unclear mechanisms. This study investigated the effects of arsenic on amyloid-β (Aβ), a peptide linked to AD pathogenesis, in differentiated SH-SY5Y neuroblastoma cells. Arsenic increased intracellular Aβ

Indexed as

AcetylcholinesteraseAmyloid beta-PeptidesAmyloid beta-Protein PrecursorArsenicNeprilysinPeptide FragmentsCell DifferentiationCell Line, TumorGPI-Linked ProteinsHumansAcetylcholinesteraseACHE protein, humanAmyloid beta-Peptidesamyloid beta-protein (1-42)Amyloid beta-Protein PrecursorArsenicGPI-Linked ProteinsNeprilysinPeptide FragmentsAcetylcholinesteraseAmyloid precursor proteinAmyloid-βArsenicNeprilysin

Identifiers

PMID41865200

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.